[ti:Researchers: Lung Damage in COVID Dead May Explain 'Long COVID']
[00:00.04]A study of the lungs of people who have died from COVID-19
[00:05.48]has found persistent and extensive lung damage in most cases.
[00:13.72]This finding may help doctors understand what is responsible
[00:19.04]for a syndrome known as ‘long COVID.'
[00:24.60]People with this condition can suffer ongoing health problems for months.
[00:31.44]A report on the study appeared in eBioMedicine,
[00:36.28]a medical journal published by The Lancet.
[00:41.28]Scientists leading the research said they found
[00:45.32]some unusual characteristics of SARS-CoV-2,
[00:50.20]the virus that causes COVID-19.
[00:54.84]These qualities may explain why it is able to cause such harm.
[01:01.96]One of the co-leaders of the work, Mauro Giacca,
[01:06.56]erves as a professor at King's College London.
[01:12.40]He said the findings seem to show that "COVID-19
[01:16.96]is not simply a disease caused by the death of virus-infected cells."
[01:23.96]In some patients, he said, the seriousness of the disease is likely the result
[01:30.48]of these "cells persisting for long periods inside the lungs."
[01:37.36]Giacca and other researchers studied tissues from the lungs,
[01:42.68]heart, liver, and kidneys of 41 patients who had COVID-19.
[01:49.92]They all died at Italy's University Hospital of Trieste
[01:55.68]between February and April 2020.
[02:00.52]Giacca spoke with Reuters news agency about the team's findings.
[02:06.60]He said that his research team found no clear signs of viral infection
[02:12.84]or long-term inflammation in other organs.
[02:18.60]But they did discover massive damage to the structure of the lungs.
[02:25.44]Healthy tissue, he noted, was "almost completely substituted by scar tissue."
[02:33.60]Giacca told Reuters that this massive damage
[02:37.32]could be one of the reasons people are suffering from long COVID.
[02:44.08]"Even if someone recovers from COVID," he added,
[02:47.64]"the damage that is done could be massive."
[02:52.80]Growing evidence suggests that a small number of COVID-19 survivors
[02:59.08]can experience some ongoing symptoms.
[03:02.92]These include extreme tiredness,
[03:06.84]unclear thinking and shortness of breath.
[03:12.56]The condition is often called "long COVID."
[03:15.92]Giacca noted that almost 90 percent of the 41 patients he studied
[03:22.96]had several characteristics unique to COVID-19.
[03:28.80]One trait was that patients had extensive blood clotting
[03:34.00]in passageways transporting blood to and from the lungs.
[03:40.00]Another was that some lung cells were very large and had many nuclei.
[03:47.84]This was a result of the combining of different cells into single large cells.
[03:56.92]The researchers also found the coronavirus
[04:00.40]was still present in many kinds of cells.
[04:04.00]Giacca said that the existence of infected cells
[04:09.36]can cause the major structural changes seen in lungs.
[04:15.64]These changes can last for several weeks or months
[04:20.00]and might, he added, explain "long COVID."
[04:25.64]I'm Anna Matteo. 更多听力请访问51VOA.COM